This volume includes a variety of methods involving electron microscopy and other biophysical methods, such as crystallography, neutron scattering, and NMR procedures for the analysis of protein-RNA or RNA-RNA interactions by cross-linking, the use of chemical, enzymatic, and immunological probes, a
Ribosomes
โ Scribed by Alexander S. Spirin (auth.)
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Leaves
- 413
- Series
- Cellular Organelles
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
Dr. Spirin is a world authority on ribosomes and has published two earlier books in this area in English.
This text is for advanced undergraduates and beginning graduate students and will cover the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.
โฆ Table of Contents
Protein Biosynthesis....Pages 3-5
Messenger RNA and the Genetic Code....Pages 7-22
Transfer RNA and Aminoacyl-tRNA Synthetases....Pages 23-45
Ribosomes and Translation....Pages 47-60
Morphology of the Ribosome....Pages 63-73
Ribosomal RNA....Pages 75-95
Ribosomal Proteins....Pages 97-116
Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure)....Pages 117-129
Functional Activities and Functional Sites of the Ribosome....Pages 133-161
Elongation Cycle, Step I: Aminoacyl-tRNA Binding....Pages 163-193
Elongation Cycle, Step II: Transpeptidation (Peptide Bond Formation)....Pages 195-211
Elongation Cycle, Step III: Translocation....Pages 213-239
Elongation Rates and its Modulation....Pages 241-259
Termination of Translation....Pages 261-270
Initiation of Translation....Pages 271-308
Translational Control in Prokaryotes....Pages 309-338
Translational Control in Eukaryotes....Pages 339-369
Cotranslational Folding and Transmembrane Transport of Proteins....Pages 371-396
Conclusion: General Principles of Ribosome Structure and Function....Pages 397-405
โฆ Subjects
Biochemistry, general;Biophysics/Biomedical Physics;Human Genetics
๐ SIMILAR VOLUMES
<p>This book is based on an advanced course of lectures on ribosome structure and protein biosynthesis that I offer at the Moscow State University. These lectures have been part of a general course on molecular biology for almost three decades, and they have undergone considerable evolution as knowl
Dr Spirin is a world authority on ribosomes and has published two earlier books in this area in English. This text is for advanced undergraduates and new graduate students and covers the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is curren
This book is based on an advanced course of lectures on ribosome structure and protein biosynthesis that I offer at the Moscow State University. These lectures have been part of a general course on molecular biology for almost three decades, and they have undergone considerable evolution as knowledg
<p>This monograph is neither a historical outline of the development of the concepts of protein biosynthesis and the structure and functions of the ribosomes, nor an exhaustive survey of the literature on these questions. The monograph is based upon an analysis of the modern trends in this field. Th