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Ribosomal protein S19 and S24 insufficiency cause distinct cell cycle defects in Diamond–Blackfan anemia

✍ Scribed by Jitendra Badhai; Anne-Sophie Fröjmark; Edward J. Davey; Jens Schuster; Niklas Dahl


Book ID
116270799
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
464 KB
Volume
1792
Category
Article
ISSN
0925-4439

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Mutations in the ribosomal protein (RP)S19 gene have been found in about 25% of the cases of Diamond-Blackfan anemia (DBA), a rare congenital hypoplastic anemia that includes variable physical malformations. Various mutations have been identified in the RPS19 gene, but no investigations regarding th