✦ LIBER ✦

Riboflavin operon of Bacillus subtilis: unusual symmetric arrangement of the regulatory region

✍ Scribed by Kil, YuriV. ;Mironovi, VladimirN. ;Gorishin, IgorYu. ;Kreneva, RimmaA. ;Perumov, DanielA.

Book ID: 104691951
Publisher: Springer
Year: 1992
Tongue: English
Weight: 402 KB
Volume: 233
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00265448

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✦ Synopsis

Seventeen cis-dominant mutations leading to riboflavin overproduction in Bacillus subtilis were localized to the region between nucleotides +37 and +159 relative to the transcription initiation site of the riboflavin operon. This region displays an unusual structure for regulatory sequences. The main part of it represents clusters of A/T and G/C-rich sequences that symmetrically blank a short inverted repeat.

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