accurate representation of the data is given in Table 1. 7. The major conclusion of this paper was that monitoring hepatitis C virus RNA levels and varying the duration of therapy can save resources without sacrificing rates of SVR. The authors used the Blackwelder test to test the noninferiority of
Ribavirin dose reduction raises relapse rate dose-dependently in genotype 1 patients with hepatitis C responding to pegylated interferon alpha-2b plus ribavirin
β Scribed by N. Hiramatsu; T. Oze; T. Yakushijin; Y. Inoue; T. Igura; K. Mochizuki; K. Imanaka; A. Kaneko; M. Oshita; H. Hagiwara; E. Mita; T. Nagase; T. Ito; Y. Inui; T. Hijioka; K. Katayama; S. Tamura; H. Yoshihara; Y. Imai; M. Kato; Y. Yoshida; T. Tatsumi; K. Ohkawa; S. Kiso; T. Kanto; A. Kasahara; T. Takehara; N. Hayashi
- Book ID
- 108886259
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 175 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1352-0504
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## Abstract The efficacy of interferon (IFN) monotherapy for nonβresponders to pegylated interferon (PEGβIFN) plus ribavirin (RBV) combination therapy is still unclear. To evaluate the impact of IFN monotherapy on biochemical response, 200 consecutive patients infected with HCV genotype 1b, who rec
In patients chronically infected with hepatitis C virus (HCV) genotype 4, the optimum duration of therapy and the predictors of sustained virologic response (SVR) have not been adequately determined. In this study, 358 patients with chronic hepatitis C genotype 4 were randomly assigned to pegylated