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Rho/Rhotekin-mediated NF-κB activation confers resistance to apoptosis

✍ Scribed by Liu, Ching-Ann; Wang, Mei-Jung; Chi, Chin-Wen; Wu, Chew-Wun; Chen, Jeou-Yuan

Book ID
110069169
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
462 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract Molecular mechanisms responsible for tumor resistance to apoptosis often involve the Fas/FasL pathway. While squamous cell carcinomas of the head and neck (SCCHN) express both Fas and FasL, their resistance to self‐induced apoptosis or apoptosis mediated by Fas agonistic antibody (CH‐11