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RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3K/Akt signaling pathway

✍ Scribed by Zhao, Hui; Yang, Jianping; Fan, Tianli; Li, Shenglei; Ren, Xuequn


Book ID
118302767
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
768 KB
Volume
33
Category
Article
ISSN
1010-4283

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## Abstract We investigated the status of the PI 3‐kinase/AKT/PTEN signaling pathway in a series of 117 head and neck squamous cell carcinomas (HNSCC) in a search for molecular alterations in genes/proteins with potential prognostic value. For this purpose, __PIK3CA__ and __AKT2__ gene amplificatio