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Rhodium-Catalyzed Reaction of 1-Alkenylboronates with Aldehydes Leading to Allylation Products

✍ Scribed by Hiroshi Shimizu; Tomohiro Igarashi; Dr. Tomoya Miura; Prof. Dr. Masahiro Murakami


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
349 KB
Volume
123
Category
Article
ISSN
0044-8249

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Ethyl trimethylsilyldiazoacetate reacts smoothly with a variety of aldehydes at 0 °C in the presence of a catalytic amount of tetrabutylammonium fluoride to produce adiazo-13-hydroxy esters in good to excellent yields. The resulting a-diazo-13-hydroxy esters can be stereoselectively transformed, by