Rhodium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of β-Ketoenamides: Efficient Access to anti 1,3-Amino Alcohols
✍ Scribed by Huiling Geng; Weicheng Zhang; Jian Chen; Guohua Hou; Le Zhou; Yaping Zou; Wenjun Wu; Xumu Zhang
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 300 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0044-8249
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## Abstract A highly efficient and enantioselective hydrogenation of unprotected β‐ketoenamines catalyzed with ruthenium(II) dichloro{(__S__)‐(−)‐2,2′‐bis[di(3,5‐xylyl)phosphino]‐1,1′‐binaphthyl}[(2__S__)‐(+)‐1,1‐bis(4‐methoxyphenyl)‐3‐methyl‐1,2‐butanediamine] {Ru[(__S__)‐xylbinap][(__S__)‐daipen]