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Rhodium-Catalyzed Diarylation of Oxalates Using Arylboron Compounds.

โœ Scribed by Sawako Miyamura; Tetsuya Satoh; Masahiro Miura


Book ID
102006933
Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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Rhodium-catalyzed asymmetric 1,4-additio
โœ Yoshiaki Takaya; Masamichi Ogasawara; Tamio Hayashi ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 265 KB

Rhodium-catalyzed asymmetric 1,4-addition to 0t,13-unsaturated ketones is effected by use of arylborates, generated in situ by lithiation of aryl bromides followed by treatment with trimethoxyborane, to give the corresponding [3-aryl ketones of up to 99% ee in high yields. The addition of I equiv. (