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RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration

✍ Scribed by Matthieu Rousseau; Marie-Hélène Gaugler; Audrey Rodallec; Stéphanie Bonnaud; François Paris; Isabelle Corre


Book ID
116302454
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
768 KB
Volume
414
Category
Article
ISSN
0006-291X

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The late onset of necrosis and fibrosis in normal tissues can be a serious consequence of radiotherapy in cancer patients. Because radiation-induced vascular injury precedes the tissue damage, vascular injury is regarded as crucial in the pathogenesis of tissue damage. An understanding of the proces