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RhoA and Rac1 signals in fMLP-induced NF-κB activation in human blood monocytes

✍ Scribed by Ling-Yu Chen; Andrzej Ptasznik; Zhixing K Pan

Book ID: 116288543
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 253 KB
Volume: 319
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.05.038

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## Abstract Although many membrane components have been described to be involved in the activation of cells by bacterial lipopolysaccharide (LPS), the question remains whether LPS, once internalized by target cells, is also capable of interacting with cytoplasmic elements in such a way that activat