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Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expression

✍ Scribed by Andrea Witteck; Ying Yao; Marcel Fechir; Ulrich Förstermann; Hartmut Kleinert


Book ID
117099845
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
545 KB
Volume
287
Category
Article
ISSN
0014-4827

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✍ Ronald G. Wilson Jr; Selma Zimmerman; Arthur M. Zimmerman 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 181 KB 👁 1 views

The purpose of this investigation was to determine the relationship of hydrostatic pressure-induced changes in the cytoarchitecture to regulation of gene expression in PC-12 cells. Hydrostatic pressure disrupts the cytoskeleton, decreases tubulin and actin mRNA levels and causes changes in the local