✦ LIBER ✦

Rho kinase inhibitors block activation of pancreatic stellate cells

✍ Scribed by Atsushi Masamune; Kazuhiro Kikuta; Mashiro Satoh; Kennichi Satoh; Tooru Shimosegawa

Book ID: 110008082
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 392 KB
Volume: 140
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705551

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Curcumin blocks activation of pancreatic

Curcumin blocks activation of pancreatic stellate cells

✍ Atsushi Masamune; Noriaki Suzuki; Kazuhiro Kikuta; Masahiro Satoh; Kennichi Sato 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB

## Abstract Activated pancreatic stellate cells (PSCs) play a pivotal role in the pathogenesis of pancreatic fibrosis and inflammation. Inhibition of activation and cell functions of PSCs is a potential target for the treatment of pancreatic fibrosis and inflammation. The polyphenol compound curcum

Increased Liver Uptake and Reduced Hepat

Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632

✍ Marike Marjolijn van Beuge; Jai Prakash; Marie Lacombe; Eduard Post; Catharina R 📂 Article 📅 2011 🏛 Springer US 🌐 English ⚖ 687 KB

Hydrogen peroxide activates activator pr

Hydrogen peroxide activates activator protein-1 and mitogen-activated protein kinases in pancreatic stellate cells

✍ Kazuhiro Kikuta; Atsushi Masamune; Masahiro Satoh; Noriaki Suzuki; Kennichi Sato 📂 Article 📅 2006 🏛 Springer 🌐 English ⚖ 358 KB

Lysophosphatidylcholine induces glial ce

Lysophosphatidylcholine induces glial cell activation: Role of rho kinase

✍ Abdullah Md. Sheikh; Atsushi Nagai; Jae K. Ryu; James G. McLarnon; Seung U. Kim; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 426 KB

## Abstract Lysophosphatidylcholine (LPC), a major phospholipid component of atherogenic oxidized LDL, is implicated in atherosclerosis and, recently, in neurodegenerative diseases. We investigated the immunomodulatory functions of LPC in the central nervous system (CNS) using both an __in vivo__ r

Green tea polyphenol (–)-epigallocatechi

Green tea polyphenol (–)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells

✍ H. Asaumi; S. Watanabe; M. Taguchi; M. Tashiro; Y. Nagashio; Y. Nomiyama; H. Nak 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 282 KB

Adenosine monophosphate–activated protei

Adenosine monophosphate–activated protein kinase modulates the activated phenotype of hepatic stellate cells

✍ Alessandra Caligiuri; Cristiana Bertolani; Cristina Tosti Guerra; Sara Aleffi; S 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 428 KB

Adiponectin limits the development of liver fibrosis and activates adenosine monophosphate-activated protein kinase (AMPK). AMPK is a sensor of the cellular energy status, but its possible modulation of the fibrogenic properties of hepatic stellate cells (HSCs) has not been established. In this stud