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Rho kinase inhibitors: A novel therapeutical intervention in asthma?

✍ Scribed by Dedmer Schaafsma; Reinoud Gosens; Johan Zaagsma; Andrew J. Halayko; Herman Meurs

Book ID
113587446
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
657 KB
Volume
585
Category
Article
ISSN
0014-2999

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## Abstract The migration of aberrant inflammatory cells into the central nervous system plays an important role in the pathogenesis of demyelinating diseases potentially through the Rho/Rho‐kinase (Rock) pathway, but direct evidence from human and animal models remains inadequate. Here we further