Rho-kinase inhibition suppresses bladder
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Mahadevan Rajasekaran; Nathan Wilkes; Steven Kuntz; Michael E. Albo
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Article
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2005
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John Wiley and Sons
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English
β 240 KB
## Abstract ## Aims Spontaneously hypertensive rats (SHR) exhibit overactive bladder (OAB) symptoms and have an upβregulated calcium sensitizing RhoA/Rhoβkinase pathway in their vascular smooth muscle tissues. This study examined the role of RhoA/Rhoβkinase pathway in bladder hyperactivity by eval