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Rho GTPases, actomyosin contractility and cell migration

✍ Scribed by C. Marshall

Book ID
119598448
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
84 KB
Volume
6
Category
Article
ISSN
1359-6349

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## Abstract The Rho GTPasesβ€”Rho, Rac and Cdc42β€”act as molecular switches, cycling between an active GTP‐bound state and an inactive GDP‐bound state, to regulate the actin cytoskeleton. It has recently become apparent that the Rho GTPases can be activated in subcellular zones that appear semi‐stable