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Rh(I)-Catalyzed Reaction of 2-(Chloromethyl)phenylboronic Acids and Alkynes Leading to Indenes

โœ Scribed by Miyamoto, Masaki; Harada, Yasuyuki; Tobisu, Mamoru; Chatani, Naoto


Book ID
121405243
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
97 KB
Volume
10
Category
Article
ISSN
1523-7060

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Asymmetric 1,4-addition of phenylboronic
โœ Yoshiaki Takaya; Masamichi Ogasawara; Tamio Hayashi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 84 KB ๐Ÿ‘ 2 views

Reaction of 2-cyclohexenone with phenylboronic acid in the presence of 3 mol% of a rhodium(I)/(S)-binap catalyst in dioxane/H2O (10/1) at 100 degrees C proceeded with high enantioselectivity to give a high yield of (S)-3-phenylcyclohexanone of up to 99% ee. The high enantioselectivity was achieved b