Rheumatologic manifestations of human parvovirus B19 infection in adults. Initial Two-Year Clinical Experience
✍ Scribed by Stanley J. Naides; Laura L. Scharosch; Frank Foto; Elizabeth J. Howard
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 984 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
✦ Synopsis
During 1987 and 1988, we identified 9 adults at the Medical and Rheumatology Services of the University of Iowa Hospitals and Clinics who had a clinical diagnosis of fifth disease; 8 of the 9 had symptoms of joint involvement. Another 12 adults with serologic positivity for anti-parvovirus B19 IgM antibody presented with polyarthralgidpolyarthritis. Patients were usually found to be seronegative for rheumatoid factor, and none developed nodules or erosive disease. Many patients with chronic disease met criteria for a diagnosis of rheumatoid arthritis. A diagnosis of parvovirus B19 infection should be considered during the initial visit of patients with polyarthralgia/polyarthritis.
Human parvovirus B19 causes childhood exanthem erythema infectiosum, or fifth disease (1-3, a similar syndrome in adults (6), a chronic arthropathy (7,8), aplastic crisis in patients with chronic hemolytic anemia (9-16), hydrops fetalis (17-20), a neonatal