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Rheumatoid arthritis: links with cardiovascular disease and the receptor for advanced glycation end products

✍ Scribed by Lisa Carroll; Suad Hannawi; Thomas Marwick; Ranjeny Thomas


Publisher
Springer Vienna
Year
2006
Tongue
German
Weight
187 KB
Volume
156
Category
Article
ISSN
0043-5341

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## Abstract ## Objective The receptor for advanced glycation end products (RAGE) binds multiple ligands, including S100 proteins, high mobility group box chromosomal protein 1 (HMGB‐1), and AGEs, all of which are present in articular cartilage. Stimulation of RAGE signaling can lead to MAP kinase