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Rheumatoid arthritis in greek and british patients. a comparative clinical, radiologic, and serologic study

✍ Scribed by A. A. Drosos; J. S. Lanchbury; G. S. Panayi; H. M. Moutsopoulos


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
366 KB
Volume
35
Category
Article
ISSN
0004-3591

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✦ Synopsis


To compare the clinical, radiologic, and serologic expression of rheumatoid arthritis (RA) in 2 different populations.

Methods. Standard protocols and assessment criteria were used in this study of 108 Greek and 107 British patients with RA.

Results. British patients had more severe articular involvement than did Greeks, as judged by the duration of morning stiffness (P C O.OOS), grip strength (P < O.OOOl), and the numbers of swollen (P C 0.001) and tender (P C 0.0001) joints. The British RA patients also had more severe joint damage on radiologic examination, as evidenced by Steinbrocker stage I11 (P C 0.005) and IV (P C 0.025) disease and had more extraarticular manifestations (P < 0.0001), including rheumatoid nodules (P C 0.


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## Abstract ## Objective Radiologic progression in rheumatoid arthritis (RA) is considered the consequence of persistent inflammatory activity. To determine whether a change in disease activity is related to a change in radiologic progression in individual patients, we investigated the longitudina