Rhesus sensitization after midtrimester genetic amniocentesis

✍ Scribed by Brandenburg, H. ;Jahoda, M. G. J. ;Pijpers, L. ;Wladimiroff, J. W. ;Opitz, John M. ;Reynolds, James F.

• Book ID: 101444085
• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: English
• Weight: 160 KB
• Volume: 32
• Category: Article
• ISSN: 0148-7299
• DOI: 10.1002/ajmg.1320320216

✦ Synopsis

In 944 Rh-negative patients who received rhesus immunoglobulin (anti-D) following genetic amniocentesis, not a single case of Rh sensitization occurred. Routine administration of a small dose (100 pg) of anti-D is effective in preventing Rh sensitization after midtrimester amniocentesis.