Rheostatic signaling by CD44 and hyaluronan
✍ Scribed by Ellen Puré; Richard K. Assoian
- Book ID
- 113528291
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 520 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0898-6568
No coin nor oath required. For personal study only.
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## Abstract This study examines the functional relationship between glioma cell production of hyaluronan (HA), known to play a role in glioma invasion, expression of its CD44 receptor, and glioma cell viability. Production of HA by CD44 positive mouse G26 and human U373 glioma cell lines was evalua
Invasion is a clinically important problem contributing to mortality and morbidity in patients with gliomas, but the mechanism(s) by which glioma cells invade surrounding brain structures is poorly understood. Various experimental models have been used in attempts to elucidate the process of glioma