Rhabdomyosarcoma with heterologous cartilage of the uterine cervix: A clinicopathologic and immunohistochemical study of an aggressive neoplasm in a young female

✍ Scribed by Perrone, Theresa ;Carson, Linda F. ;Dehner, Louis P.

• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 593 KB
• Volume: 18
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/mpo.2950180116

✦ Synopsis

Abstract

This report concerns a 20‐year‐old female who had a F.I.G.O. stage I rhabdomyosarcoma (sarcoma botryoides) of the cervix with a predominant embryonal pattern and heterologous cartilage that pursued an aggressive course despite surgery and chemotherapy. The patient had a pelvic recurrence, developed pulmonary metastases 15 months after diagnosis, and died 6 months later. Despite some previously published favorable prognostic assessments about this unique variant of cervical rhabdomyosarcoma, our limited experience would interject a note of caution, especially in the presence of a focal alveolar pattern and invasion of lymphatics in the cervix.