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Rhabdomyolysis without neuroleptic malignant syndrome induced by additional treatment of risperidone

✍ Scribed by Norio Yasui; Tsuyoshi Kondo; Koichi Otani; Sunao Kaneko

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 65 KB
Volume: 13
Category: Article
ISSN: 0885-6222
DOI: 10.1002/(sici)1099-1077(1998120)13:8<575::aid-hup42>3.0.co;2-h

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✦ Synopsis

This is the ®rst case report of rhabdomyolysis without neuroleptic malignant syndrome induced by additional treatment of risperidone. The manifestations of this side eect were symptoms of myalgia, muscle weakness and redcoloured urine with ®ndings of markedly elevated levels of creatine kinase and myoglobin in serum as well as myoglobinuria. Early diagnosis of rhabdomyolysis, immediate discontinuation of risperidone and administration of dantrolene had favourable eects on the course of the treatment of this side eect.

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