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Rhabdomyolysis associated with mania in late life

✍ Scribed by Nabil Kotbi; Nahla Mahgoub; Josephine Mokonogho; Robert Young

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 38 KB
Volume: 24
Category: Article
ISSN: 0885-6230
DOI: 10.1002/gps.2270

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✦ Synopsis

Dear Editor

Rhabdomyolysis is a potentially fatal condition that follows skeletal muscle injury and leads to serious complications such as renal failure (Johnson et al., 1987;Jermain and Crismon, 1992). Skeletal muscle injury triggers the release of intracellular contents including creatine phosphokinase (CPK) and myoglobin which is manifested by muscle pains and dark urine (Johnson et al., 1987;Jermain and Crismon, 1992).

Prevalence of rhabdomyolysis is rare and descriptions are confined mostly to case reports (Johnson et al., 1987;Jermain and Crismon, 1992). The incidence of rhabdomyolysis in psychiatric patients is unknown (Johnson et al., 1987). Nevertheless, several risk factors make psychiatric patients vulnerable to develop rhabdomyolysis. These factors include catatonia, agitation, alcohol abuse, and neuroleptics (

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