Rhabdoid tumor of the kidney: Complete remission induced by cis-platinum and adriamycin

✍ Scribed by Roper, Maryann ;Parmley, Richard T. ;Crist, William M. ;Kelly, David R. ;Hyland, Caryl H. ;Salter, Merle

• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: English
• Weight: 459 KB
• Volume: 9
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/mpo.2950090211

✦ Synopsis

Abstract

A 4‐month‐old male infant with Stage I rhabdoid tumor of the kidney at presentation subsequently developed pulmonary metastatic disease shortly after diagnosis and initiation of Vincristine and Actinomycin D chemotherapy. The patient was then treated with cis‐platinum and Adriamycin. Within 28 days he achieved a complete remission which was maintained for 5 months. Subsequent recurrent pulmonary lesions failed to regress with radiotherapy and high‐dose cyclophosphamide when used as single sequential agents. Further clinical trials with cis‐platinum and Adriamycin seem warranted since prognosis with this tumor is poor and successful chemotherapy after metastatic dissemination has not been previously reported.