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RG-004 Detection of mutations in the dystrophin gene via DHPLC screening

✍ Scribed by TJ Chen; J Du; LY Li; W Li; GX Lu


Book ID
119612453
Publisher
Reproductive Healthcare Ltd
Year
2006
Tongue
English
Weight
107 KB
Volume
12
Category
Article
ISSN
1472-6491

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Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked neuromuscular disorders associated with alterations in the dystrophin gene. Analysis of 45 DMD/BMD patients has identified 18 patients with no deletion in the dystrophin gene. Heteroduplex analysis (HD), single strand