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Revisiting Thymic Positive Selection and the Mature T Cell Repertoire for Antigen

✍ Scribed by Vrisekoop, Nienke; Monteiro, João P.; Mandl, Judith N.; Germain, Ronald N.

Book ID
126506798
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
851 KB
Volume
41
Category
Article
ISSN
1074-7613

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The selection of developing and mature alpha beta T cells, by intrathymic and extra-thymic ligands expressed on cells of hemopoietic and other origins, has been studied in a variety of systems. These experiments have increased our knowledge of the selection of alpha beta T cells in the thymus, in th