A novel alkaloid, prianosin A (l), with potent antineoplastic activity has been isolated from the Okinawan marine sponge Pianos melanos. Its absolute stereostructure was determined by single crystal x-ray diffraction analysis.
Revised structures of prianosins C and D, antineoplastic alkaloids from the Okinawan marine sponge Prianos melanos
β Scribed by Jun'ichi Kobayashi; Jie-fei Cheng; Shosuke Yamamura; Masami Ishibashi
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 179 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Theowpolide B (2) end C (J), hvo new macrolidea with vclrious functionalitiea, have beon isolated from theOkinawpnm;rrine8pongeI)uoncllasp.rmdtbeirstrucbneselucidatsdonthsbrsisof~ icdahcls well= chemical degrndstion e.x~ts. Ths absoh confiSur&ms oftha tehnal chirai centerof~lides A (l), B (2), and C
A new b-carboline alkaloid, eudistomidin G (1), has been isolated from the Okinawan marine tunicate Eudistoma glaucus, and the structure was elucidated from spectroscopic data. Furthermore, the structure of eudistomidin B (2), which has been isolated from the same tunicate, was revised from 2a to 2b
## Abstract Isolation and structure elucidation of eudistomidin G (Ia) is described.
Ah&act: 'zhne new cytotoxic and annmicmbii pepribes, discodemiins F (6). G ( 7). and H (8). have heen isolated tiWithemarinesp~neeDircodcnnia kiiensi.r. 'kslmctmsof64waede&midbyin~onof~dala mdchanicslde~dathegreaation. S~ofdisEoderminsA-DwaerevisedmthebasisofNMRdataandprotcinscqucnce analysis