Review The Defense Mechanisms in Mammalian Cells against Oxidative Damage in Nucleic Acids and their Involvement in the Suppression of Mutagenesis and Cell Death
β Scribed by Nakabeppu, Yusaku; Tsuchimoto, Daisuke; Furuichi, Masato; Sakumi, Kunihiko
- Book ID
- 121495886
- Publisher
- Informa plc
- Year
- 2004
- Tongue
- English
- Weight
- 124 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1071-5762
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The interaction of antioxidants can provide an essential protection against the damaging effects of free radicals. Beneficial interactions include radioprotection, protection against acute toxicity of chemicals, and antimutagenic and anticarcinogenic activity. The present study was undertaken to eva
## Abstract Several __in vitro__ studies showed that free radical scavengers possess chemopreventive properties against mycotoxinβinduced cell damage which are at least partially associated with the induction of phase II detoxifying enzymes and antioxidant enzymes like glutathione __S__βtransferase