Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor
โ Scribed by Philippe Dostert; Margherita S. Benedetti; Italo Poggesi
- Book ID
- 118599640
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 885 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0924-977X
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๐ SIMILAR VOLUMES
A double-blind, randomized, four-way crossover study was performed to assess the CNS eects of reboxetine, a unique selective noradrenaline reuptake inhibitor (NRI). Eighteen volunteers received reboxetine (1 or 3 mg), imipramine (75 mg) or placebo at weekly intervals. Pharmaco-electroencephalography
Milnacipran is a novel antidepressant agent which selectively inhibits the reuptake of serotonin and noradrenaline without directly aecting postsynaptic receptor sites. The biochemical and pharmacological proยฎle of milnacipran suggested that the drug would be therapeutically eective and well tolerat