Explaining ADAGIO: A critical review of
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Peter Jenner; J. William Langston
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Article
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2011
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John Wiley and Sons
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English
β 201 KB
## Abstract The ADAGIO study demonstrated a symptomatic benefit for rasagiline in early Parkinson's disease (PD) and suggested a diseaseβmodifying effect. Evidence indicates that mitochondrial dysfunction plays a role in the pathogenesis of PD and that this may be the site of effect for rasagiline.