✦ LIBER ✦

Review of the development of methodology for evaluating the human allergenic potential of novel proteins

✍ Scribed by Steve L. Taylor

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 167 KB
Volume: 50
Category: Article
ISSN: 1613-4125
DOI: 10.1002/mnfr.200500275

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Safety assessment of novel proteins in genetic‐engineered foods is a key component of the overall safety evaluation for these products. Since allergens are typically proteins, assessment of the potential allergenicity of the novel proteins in genetically engineered foods is critical. This article reviews methods available to assess the potential allergenicity of novel proteins, as well as problems and deficiencies in the existing methods. The role of bioinformatics and knowledge of allergenic epitopes in developing new approaches to this problem is discussed.

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