✦ LIBER ✦

Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasms

✍ Scribed by A.A. Gumbs; P.S. Moore; M. Falconi; C. Bassi; S. Beghelli; I. Modlin; A. Scarpa

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 242 KB
Volume: 81
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.10142

No coin nor oath required. For personal study only.

✦ Synopsis

Pancreatic endocrine neoplasms (PENs) are rare tumors, and little is known about their genetic and chromosomal alterations. Elucidation of the molecular events involved in PEN carcinogenesis has been hindered by the fact that PENs have been considered a single disease entity. The emergence of novel molecular characterization strategies has, however, made it apparent that these lesions exhibit diverse molecular fingerprints, which will facilitate the precise delineation of PEN prognosis, histopathology, and carcinogenesis.

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