✦ LIBER ✦

Review of photodynamic therapy for gastrointestinal tumours in the past 6 years in China

✍ Scribed by M.L. Jin; B.Q. Yang; W. Zhang; P. Ren

Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 374 KB
Volume: 7
Category: Article
ISSN: 1011-1344
DOI: 10.1016/1011-1344(90)85145-m

No coin nor oath required. For personal study only.

✦ Synopsis

Patients (142) with advanced gastrointestinal (GI) cancers were treated by photodynamic therapy (PDT) from September 1982 to December 1988. Haematoporphyrin derivative (HpD) (5 mg kg-1) was intravenously given 48-72 h prior to PDT. The light source was an argon dye laser emitting at 630 nm. The entire tumour was irradiated with a light dose of 100-250 J cm-2. Fifteen patients (10.6%) showed complete response (CR), 53 (37.3%) showed partial response (PR) and 32 (22.5%) showed mild response (MR). The clinical results show that the estimated energy dose (EED) of 200-250 J cm-2 is appropriate. All patients were treated by PDT and adjuvant chemotherapy showing good results with a follow-up of 1-5 years; 13 out of 15 patients in the CR group are alive (86.7%); 12 patients survived more than 2 years (8.8%).

📜 SIMILAR VOLUMES

Challenges for photodynamic therapy in t

Challenges for photodynamic therapy in the treatment of gastrointestinal tumours

✍ T. Patrice 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 212 KB

Adjuvant therapy for gastric carcinoma p

Adjuvant therapy for gastric carcinoma patients in the past 15 years : A review of Western and Oriental trials

✍ Ken Shimada; Jaffer A. Ajani 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 2 views

## Background: The early detection of gastric carcinoma is neither feasible nor practiced around the world, except on a limited basis in japan. thus, because gastric carcinoma is detected later in most patients throughout the world, those who undergo curative resection still remain at high risk for

Experimental grounds for using chlorin ρ

Experimental grounds for using chlorin ρ6 in the photodynamic therapy of malignant tumors

✍ G.A. Kostenich; I.N. Zhuravkin; E.A. Zhavrid 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 684 KB

The toxicity, pharmacokinetics and antitumour effect of chlorin e6 after light irradiation were studied. The LD50 value of chlorin e6 in C3H mice is 189 +/- 9 mg kg-1 and in Wistar white rats is 113 +/- 18 mg kg-1 14 days after intraperitoneal injection. The concentration of chlorin e6 in blood, liv

Use of Irradiation for Therapy of Retino

Use of Irradiation for Therapy of Retinoblastoma in Children More Than 1 Year Old: The St. Jude Children's Research Hospital Experience and Review of Literature

✍ Fontanesi, James ;Pratt, Charles B. ;Hustu, H. Omar ;Coffey, Douglas ;Kun, Larry 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 520 KB

Synthesis of the Dimethyl Ester of 2'-Cy

Synthesis of the Dimethyl Ester of 2'-Cyano-8'-formyl-N'-methyl-1',1a',5a',6'-tetrahydroacrido[4,5,5a,6-bcd]-Annulated 2,3-Dihydromesoporphyrin – A Novel System with Outstanding Properties as Basis for Photodynamic Therapy in the Far-Red Region of the Visible Spectrum

✍ Richard N S. van der Haas; Siu-Ha Tang; Beatriz Arenas Hernández; Robertus L. P. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB 👁 2 views

The Synthesis of the Dimethyl Ester of Q

The Synthesis of the Dimethyl Ester of Quino[4,4a,5,6-efg]-Annulated 7-Demethyl-8-deethylmesoporphyrin and Three of Its Isomers with Unprecedented peri-Condensed Quinoline Porphyrin Structures. Molecules with Outstanding Properties as Sensitizers for Photodynamic Therapy in the Far-Red Region of the Visible Spectrum

✍ Richard N. S. van der Haas; Robertus L. P. de Jong; Maryam Noushazar; Kees Erkel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB