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Review of mechanistic studies relevant to the potential carcinogenicity of asphalts

✍ Scribed by Ceinwen A. Schreiner

Book ID
113965676
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
297 KB
Volume
59
Category
Article
ISSN
0273-2300

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Cellular uptake of Cr(VI), followed by its reduction to Cr(III) with the formation of reactive Cr(V/IV) intermediates, is a generally accepted cause of Cr(VI)-induced genotoxicity and carcinogenicity. Recently, Cr(III) oxidation to Cr(V) and/or Cr(VI) in biological systems came into consideration as