Review of clinical and haematological response to low-dose cytosine arabinoside in acute myeloid leukaemia
β Scribed by Mordechai Shtalrid; Joseph Lotem; Leo Sachs; Alain Berrebi
- Book ID
- 114790791
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 635 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0902-4441
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High dose cytosine arabinoside (HD-AraC) was evaluated 1) as remission induction therapy for refractory acute leukemia and high risk AML, 2) as augmentation therapy for acute leukemia, and 3) as conditioning therapy prior to allogeneic bone marrow transplantation for acute leukemia. Seven of 10 pati
Clofarabine (40Β mg/m^2^/dayβΓβ5) and high-dose cytosine arabinoside (Ara-C, 1β2Β g/m^2^/dayβΓβ5) were used in 10 men and 11 women, at a median age of 45 (22β62)βyears, with refractory (__N__β=β4) and relapsed (__N__β=β17) acute myeloid leukaemia, after a median of 3 (2β5) prior regimens. Grade 4 myel