## Abstract Oncogenic activation in primary murine fibroblasts initiates a senescenceβlike cell cycle arrest that depends on the p53 tumor suppressor pathway. Conditional p53 activation efficiently induced a reversible cell cycle arrest but was unable to induce features of senescence. In contrast,
REVIEW ARTICLE. p53: GUARDIAN OF CELLULAR SENESCENCE
β Scribed by WYNFORD-THOMAS, DAVID
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 369 KB
- Volume
- 180
- Category
- Article
- ISSN
- 0022-3417
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