Review article: detection and management of hereditary non-polyposis colorectal cancer (Lynch syndrome)
โ Scribed by D. RAMSOEKH; M. E. VAN LEERDAM; A. WAGNER; E. J. KUIPERS
- Book ID
- 108605121
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 114 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0269-2813
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To identify characteristics of gastric cancer associated with hereditary non-polyposis colorectal cancer (HNPCC), we gathered clinical data and tumor samples relating to patients recorded in the Finnish HNPCC registry. Our series included 51 families with a characterized mutation and/or that met the
A s of 1999, it is possible to test selected subjects for carriage of germline mutations in genes responsible for familial adenomatous polyposis (FAP), 1,2 hereditary nonpolyposis colorectal cancer (HNPCC), 3,4 Peutz-Jeghers syndrome, 5 and juvenile polyposis. 6,7 These diseases are heterogeneous ph