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Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas

✍ Scribed by Nunung Nur Rahmah; Keiichi Sakai; Jun Nakayama; Kazuhiro Hongo

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
238 KB
Volume
33
Category
Article
ISSN
0344-5607

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## Abstract ## BACKGROUND The recently described __re__version‐inducing __c__ysteine‐rich protein with __K__azal motifs (RECK) inhibits membrane Type 1 matrix metalloproteinase (MMP‐14), MMP‐2, and MMP‐9 secretion and enzymatic activity. Its expression is essential for normal vasculogenesis. Down‐