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Reversible parkinsonism following heroin pyrolysate inhalation is associated with tetrahydrobiopterin deficiency

✍ Scribed by Simon Heales; Francesca Crawley; Peter Rudge


Book ID
102503190
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
126 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

A patient who inhaled heroin vapour (chasing the dragon), resulting in temporary parkinsonism, is described. A reversible deficiency of tetrahydrobiopterin, causing altered dopamine metabolism, is demonstrated as the metabolic basis of this aspect of the encephalopathy. © 2004 Movement Disorder Society