Reversible paralysis with status asthmaticus, steroids, and pancuronium: Clinical electrophysiological correlates
✍ Scribed by Jeremy Road; Gordon Mackie; Tian-Xi Jiang; Heather Stewart; Andrew Eisen
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 26 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
✦ Synopsis
Prolonged neuromuscular weakness has been identified after neuromuscular blockade in intensive care unit patients on mechanical ventilation. Previously reported electromyographic studies in these patients documented both neurogenic features and features consistent with a myopathy. We recorded sequential electrophysiological parameters during recovery from neuromuscular blockade in 5 patients with clinical weakness. An evolving pattern was identified. The early features were in keeping with previous reports of neurogenic changes, and this evolved into features consistent with a primary myopathy. Several potential underlying mechanisms are discussed.