Reversible G1 arrest in the cell cycle of human lymphoid cell lines by dimethyl sulfoxide
โ Scribed by Masaji Sawai; Kozo Takase; Hirobumi Teraoka; Kinji Tsukada
- Book ID
- 115892477
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 662 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Staurosporine, a rnicrobial-derived protein kinase inhibitor, reversibly blocked non-synchronized, replicatingcultures of the human lung epithelial cell line EKVX in the G1 phase of cell cycle and inhibited DNA synthesis and cell replication. The mechanism of this cell-cycle arrest in EKVX cells by
## M dexamethasone results in inhibition of growth and rapid loss of cell viability after a delay of approximately 18 to 24 hours. Analysis of dexamethasonetreated cells by flow-microfluorometry showed that they were arrested in the GI phase of the cell cycle. Loss of cell viability began at the s