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Reversible dissociation of zinc in bovine carbonic anhydrase

✍ Scribed by Sven Lindskog; Bo G. Malmström

Book ID
118847231
Publisher
Elsevier Science
Year
1960
Tongue
English
Weight
228 KB
Volume
2
Category
Article
ISSN
0006-291X

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✍ Alice Y. Romans; Mary E. Graichen; C.H. Lochmuller; Robert W. Henkens 📂 Article 📅 1978 🏛 Elsevier Science ⚖ 461 KB

The kinetics of dissociation of Zn 2+ from the metalloenzyme carbonic anhydrase was measured over a range of pH, temperature, and acetate concentration. The rate of dissociation is extremely slow at neutral pH (tl/2 ~ 3 years, 4°C), but increases in almost direct proportion to the hydrogen ion conce