𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reversible commitment of neural and epidermal progenitor cells during embryogenesis of Drosophila melanogaster

✍ Scribed by Technau, Gerhard M. ;Becker, Thomas ;Campos-Ortega, Jose A.

Book ID
104757202
Publisher
Springer-Verlag
Year
1988
Tongue
English
Weight
1018 KB
Volume
197
Category
Article
ISSN
1432-041X

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✦ Synopsis

Cell-cell interactions are involved in mediating developmental fate. An example is the decision of the neuroectodermal cells of Drosophila to develop as neural or epidermal progenitors, where cellular interactions participate in the process of acquisition of either cell fate. The results of heterochronic cell transplantations we describe here suggest that both neuroblasts and epidermoblasts are not irreversibly committed to a particular developmental fate. Rather, they retain the ability to interact with neighbouring cells and, under our experimental conditions, are capable of switching their fate during a relatively long period of time, i.e. until the end of embryonic stage 11.

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