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Reversible arrest of Chinese hamster cells in G1 by partial deprivation of leucine

โœ Scribed by L.P. Everhart; D.M. Prescott

Book ID
118876104
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
379 KB
Volume
75
Category
Article
ISSN
0014-4827

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Arrest of chinese hamster cells in G2 fo
Arrest of chinese hamster cells in G2 following treatment with the anti-tumor drug bleomycin
โœ Robert A. Tobey ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 505 KB

Upon addition of bleomycin (BLM) to suspension cultures of Chinese hamster cells (line CHO), cells closer to prophase than 56 minutes continue dividing at the normal rate, whereas cells at earlier positions in the cell cycle either fail to reach mitosis altogether (at 200 pglml) or enter mitosis and