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Reversibility of the Tryptophanase Reaction: Synthesis of Tryptophan from Indole, Pyruvate, and Ammonia

✍ Scribed by Takehiko Watanabe and Esmond E. Snell


Book ID
123650962
Publisher
National Academy of Sciences
Year
1972
Tongue
English
Weight
772 KB
Volume
69
Category
Article
ISSN
0027-8424

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Synthetic studies of N-reverse prenylate
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The efficient method for the synthesis of N-1,1-dimethyl-2-propenyl (reverse prenyl) indole was developed by the N-propargylation of the indoline, partial hydrogenation of the terminal alkyne, and oxidation to the indole using chemical manganese dioxide (CMD). This method was used for the synthesis