✦ LIBER ✦

Reversibility of posttransplantation diabetes mellitus following liver transplantation

✍ Scribed by James D. Perkins

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 88 KB
Volume: 15
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21901

No coin nor oath required. For personal study only.

✦ Synopsis

Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persistent PTDM patients, they were characterized by younger age at the time of transplantation (49 Ϯ 7 vs. 53 Ϯ 8 yr, P Ͻ 0.05), longer time before the development of PTDM (44 Ϯ 59 vs. 13 Ϯ 20 days, P Ͻ 0.05), lower rate of hepatitis c virus seropositivity (0.0 vs. 9.4%, P Ͻ 0.05), and use of mycophenolate mofetil (59.5 vs. 28.1%, P Ͻ 0.05). Among these risk factors, age at the time of transplantation is the single independent predictive factor associated with the reversibility of PTDM.

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