Reversibility of clearance impairment after subchronic test toner inhalation

Impaired autophagic clearance after cold

Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning

✍ Thomas Minor; Judith Stegemann; Andreas Hirner; Martina Koetting 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 349 KB

Fatty livers are particularly susceptible to mitochondrial alterations after cold preservation. We thus aimed to improve graft integrity by brief hypothermic oxygenation prior to warm reperfusion. Macrovesicular steatosis was induced in rat livers by fasting and subsequent feeding of a fat-free diet