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Reversed-phase liquid chromatographic determination of enantiomers of atenolol in rat plasma using derivatization with Marfey's reagent

โœ Scribed by Ravi Bhushan; Shivani Tanwar


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
137 KB
Volume
23
Category
Article
ISSN
0269-3879

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Indirect resolution of baclofen enantiom
โœ Ravi Bhushan; Virender Kumar ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 120 KB ๐Ÿ‘ 1 views

A high-performance liquid chromatographic (HPLC) method was developed for chiral assay of baclofen enantiomers in pharmaceutical formulations using an indirect approach. Baclofen enantiomers were derivatized with Marfey's reagent (FDNP-L-Ala-NH 2 ) and its structural variants FDNP-L-Phe-NH 2 , FDNP-